Regulatory Heptapeptide

Selank 10mg

A synthetic analogue of the immunomodulatory peptide tuftsin. This advanced 7-amino acid sequence (C₃₃H₅₇N₁₁O₉) is extensively researched for its pronounced nootropic and anxiolytic properties.

Molecular Engineering Data

Molecular FormulaC₃₃H₅₇N₁₁O₉

Molecular Weight751.88 g/mol

CAS Registry129954-34-3

Physical StateAcetate Salt Solid

Primary MechanismEnkephalinase Inhibition

Assay (HPLC)>99.0% Purity

Neuromodulatory Cascade

Selank represents a unique class of neurotropic peptides. Unlike classical benzodiazepines, it modulates the GABAergic system while simultaneously inhibiting the degradation of endogenous enkephalins. This dual-action pathway allows researchers to observe significant reductions in stress-induced behavioral models alongside enhanced cognitive performance metrics, without the sedative profiles typical of conventional anxiolytics.

BDNF
Neurogenesis Factor

Observed to significantly promote the expression of Brain-Derived Neurotrophic Factor in the hippocampus, aiding memory consolidation.

ENK
Enkephalinase Inhibition

Prolongs the half-life of endogenous enkephalins in the bloodstream, contributing to its stable and pronounced anxiolytic profile.

Structural Blueprint

The 751.88 Da structure (Thr-Lys-Pro-Arg-Pro-Gly-Pro) extends the half-life of the naturally occurring tuftsin peptide. By adding a Pro-Gly-Pro sequence to the C-terminus, the molecule gains significant metabolic stability and resistance to rapid enzymatic degradation in vivo.

Selank Structure

Pharmacological Benchmarks

Base Origin: Human Tuftsin Analogue
Nootropic Action: BDNF & Serotonin Modulation
Anxiolytic Profile: Enkephalin Preservation
Sedative Traits: None Observed
Cognition: Enhanced learning acquisition

Key Research Benchmarks

In preclinical models, Selank is extensively investigated for its targeted effects on Cognitive Enhancement and Stress Attenuation. Researchers map the stabilization of neurotransmitter levels (serotonin, norepinephrine, dopamine) to determine its volumetric efficacy in behavioral and learning paradigms.

Anxiolysis
Observing the mitigation of stress responses and anxiety without corresponding motor or cognitive impairment.

Memory Consolidation
Analysis of learning acquisition and the stability of memory traces under peptide-induced nootropic conditions.

Laboratory Protocol & Handling

Storage & Stability
Supplied lyophilised for maximum sequence integrity during logistics.

Dry Storage: -20°C for >12 months; 2-8°C for <6 months.
Liquid Stability: Must be refrigerated (2-8°C) once reconstituted.
Solubility: Water (1mg/ml) or sterile physiological saline.

Reconstitution SOP
Strict adherence to laboratory SOPs is required to maintain the 7-amino acid chain.

Solvent: Sterile Bacteriostatic Water or PBS.
Technique: Slow sidewall induction; do not agitate the puck.
Unit Sizes: 10mg precision research configurations.

Strict Laboratory Compliance Notice

WARNING: This compound is a chemical reagent supplied exclusively for in-vitro and in-vivo laboratory research. It is NOT a drug, medication, or food supplement. Strictly prohibited for human or veterinary administration. Lawful handling is the sole responsibility of the professional user. HRS Distribution assumes no liability for applications outside of laboratory scientific research.