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TB500 10mg – Research Compound

£30.00

Currently out of stock (available to purchase on backorder). Estimated delivery for Backorders: 12th June 2026 (subject to change)

SKU: TB500 Categories: ,
Cytoskeletal Modulating Peptide

TB-500 10mg

A potent synthetic analogue of the naturally occurring healing protein Thymosin Beta-4. This complex 43-amino acid sequence (C212H350N56O78S) is heavily researched for its profound ability to upregulate actin and facilitate rapid tissue repair.

TB-500 Vial
Molecular Engineering Data
Molecular FormulaC212H350N56O78S
Molecular Weight4963.44 g/mol
CAS Registry77591-33-4
Physical StateAcetate Salt Solid
Primary MechanismActin Sequestration
Assay (HPLC)>99.0% Purity

Cellular Migration Cascade

TB-500 exerts its primary effects by binding directly to actin, a vital protein that forms the cellular cytoskeleton. By sequestering actin monomers, it dynamically regulates cell structure, mobility, and proliferation. This targeted mechanism allows researchers to observe significantly accelerated wound healing, the formation of new blood vessels, and reduced inflammation in localized tissue damage models.

Actin
Upregulation Factor

Drives cellular motility and structural repair by dynamically controlling the polymerization of actin filaments across damaged tissue sites.

VEGF
Angiogenesis Support

Promotes the localized formation of new blood vessels, drastically enhancing nutrient delivery and oxygenation to hypoxic or traumatized tissues.

Structural Blueprint

The 4963.44 Da structure represents the complete 43-amino acid sequence of Thymosin Beta-4. Its unique molecular geometry and high solubility allow it to travel efficiently through systemic circulation, targeting areas of localized inflammation and physical trauma with exceptional affinity.

TB-500 Structure

Pharmacological Benchmarks
  • Base Origin: Endogenous Thymus Peptide
  • Primary Action: Actin Sequestration
  • Tissue Repair: Accelerated Wound Closure
  • Inflammation: Localized Cytokine Reduction
  • Cellular Target: Cytoskeleton & Endothelium

Key Research Benchmarks

In preclinical models, TB-500 is extensively investigated for its targeted effects on Skeletal Muscle Regeneration and Cardioprotection. Researchers map the rapid migration of stem cells and endothelial cells to determine its volumetric efficacy in combating fibrosis and tissue necrosis.

Endothelial Repair
Observing the rapid migration of endothelial cells to sites of vascular or muscular injury, facilitating complete structural restoration.
Fibrosis Mitigation
Analysis of scar tissue reduction and the preservation of muscle flexibility and cellular elasticity post-trauma.

Laboratory Protocol & Handling
Storage & Stability
Supplied lyophilised for maximum sequence integrity during logistics.

  • Dry Storage: -20°C for >12 months; 2-8°C for <6 months.
  • Liquid Stability: Must be refrigerated (2-8°C) once reconstituted.
  • Solubility: Water (1mg/ml) or sterile physiological saline.
Reconstitution SOP
Strict adherence to laboratory SOPs is required to maintain the 43-amino acid chain.

  • Solvent: Sterile Bacteriostatic Water or PBS.
  • Technique: Slow sidewall induction; do not agitate the puck.
  • Unit Sizes: 10mg precision research configurations.

Strict Laboratory Compliance Notice

WARNING: This compound is a chemical reagent supplied exclusively for in-vitro and in-vivo laboratory research. It is NOT a drug, medication, or food supplement. Strictly prohibited for human or veterinary administration. Lawful handling is the sole responsibility of the professional user. HRS Distribution assumes no liability for applications outside of laboratory scientific research.

© 2026 | HRS DISTRIBUTION | UK DISPATCHED

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TB500 10mg - Research CompoundTB500 10mg – Research Compound
£30.00

Currently out of stock (available to purchase on backorder). Estimated delivery for Backorders: 12th June 2026 (subject to change)

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