Gastric Pentadecapeptide

BPC-157 10mg

A synthetic 15-amino acid sequence derived from human gastric juice. This highly stable pentadecapeptide (C₆₂H₉₈N₁₆O₂₂) is extensively researched for its profound systemic cytoprotective properties and accelerated tissue repair mechanisms.

Molecular Engineering Data

Molecular FormulaC₆₂H₉₈N₁₆O₂₂

Molecular Weight1419.53 g/mol

CAS Registry137525-51-0

Physical StateAcetate Salt Solid

Primary MechanismAngiogenesis & Cytoprotection

Assay (HPLC)>99.0% Purity

Angiogenic Healing Cascade

BPC-157 represents a cornerstone in regenerative peptide research. By potently upregulating Vascular Endothelial Growth Factor (VEGF) and modulating the nitric oxide system, researchers observe the rapid formation of new blood vessels. This sustained angiogenic response is critical for delivering oxygen and nutrients to avascular tissues, significantly accelerating the healing of tendons, ligaments, and the gastrointestinal lining.

VEGF
Vascular Endothelial Growth

Directly stimulates the expression of VEGF, driving the creation of new localized capillary networks to bypass damaged or necrotic vascular structures.

eNOS
Nitric Oxide Modulation

Stabilizes endothelial nitric oxide synthase, protecting the vascular lining from oxidative stress and maintaining optimal blood pressure during the repair phase.

Structural Blueprint

The 1419.53 Da structure (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) is remarkably stable. Its unique sequence grants it exceptional resistance to enzymatic degradation, allowing it to remain highly active even in highly acidic environments, making it a primary candidate for in-vivo gastric and intestinal research models.

BPC-157 Structure

Pharmacological Benchmarks

Base Origin: Human Gastric Juice Protein
Primary Action: Systemic Cytoprotection
Musculoskeletal: Tendon and Ligament Repair
Gastrointestinal: Ulcer Healing and Mucosal Defense
Cellular Target: Endothelium and Fibroblasts

Key Research Benchmarks

In preclinical models, BPC-157 is extensively investigated for its targeted effects on Musculoskeletal Trauma and Gut Barrier Integrity. Researchers map the rapid proliferation of fibroblasts and the accelerated closure of wounds to determine its volumetric efficacy in comprehensive tissue restoration.

Connective Tissue Repair
Observing the rapid outgrowth and survival of tendon fibroblasts, alongside accelerated recovery in models of induced Achilles tendon rupture or muscle transection.

Mucosal Defense
Analysis of intestinal permeability reduction and the profound protection of the gastric lining against NSAID-induced lesions and oxidative damage.

Laboratory Protocol & Handling

Storage & Stability
Supplied lyophilised for maximum sequence integrity during logistics.

Dry Storage: -20°C for >12 months; 2-8°C for <6 months.
Liquid Stability: Must be refrigerated (2-8°C) once reconstituted.
Solubility: Sterile Bacteriostatic Water or PBS.

Reconstitution SOP
Strict adherence to laboratory SOPs is required to maintain the 15-amino acid chain.

Solvent: Sterile Bacteriostatic Water or PBS.
Technique: Slow sidewall induction; do not agitate the puck.
Unit Sizes: 10mg precision research configurations.

Strict Laboratory Compliance Notice

WARNING: This compound is a chemical reagent supplied exclusively for in-vitro and in-vivo laboratory research. It is NOT a drug, medication, or food supplement. Strictly prohibited for human or veterinary administration. Lawful handling is the sole responsibility of the professional user. Smell.Fit and HRS Distribution assume no liability for applications outside of laboratory scientific research.