Melanotan 1 10mg
The benchmark in photobiology research. Afamelanotide (C78H111N21O19) is a potent, selective MC1R agonist designed for investigating melanogenesis and cellular UV-protective response.
Developed at the University of Arizona in the 1980s, Melanotan 1 was engineered to address the metabolic instability of natural alpha-melanocyte stimulating hormone (α-MSH). By substituting specific amino acids, researchers created a linear 13-amino acid analogue with a significantly extended half-life and higher affinity for the Melanocortin-1 receptor (MC1R).
Target Specificity
MT-1 exhibits primary selectivity for MC1R, minimizing the off-target MC3R and MC4R activation observed in cyclic analogues.
Potency Factor
Exhibits approximately 26 times the melanotropic activity of natural α-MSH in in-vitro assays.
Melanotan 1 stimulates the synthesis of Eumelanin through the activation of the MC1R/cAMP pathway. This cascade increases tyrosinase activity within melanocytes, providing a fundamental baseline for photodermatology research.
Lyophilised MT-1 is highly stable but sequence integrity is temperature-dependent.
- Dry Storage: -20°C (Up to 24 Months).
- Ambient: Stable for up to 60 days in dry transit.
- Liquid State: 2-8°C (Use within 21 days).
Readily soluble in standard laboratory buffers.
- Solvent: Sterile Bacteriostatic Water or Saline.
- Technique: Slow side-wall flow to prevent foaming.
- Visual Check: Clear, colourless solution upon dissolution.
WARNING: This compound is a chemical reagent supplied exclusively for in-vitro laboratory research and biochemical assays. It is NOT a drug, medication, or food supplement. Strictly prohibited for human or veterinary administration. Lawful handling is the sole responsibility of the professional user.
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